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Nat Commun 2015;6:6734

This Ca 2+ inflow may also be involved in VSOR activation, because VSOR was shown to be activated by ROS (Shimizu et al., 2004

5 BusseyT

2 Both alone and combined with other therapeutic agents, ICIs have contributed to promising outcomes in patients with NSCLC, which have led to 6 ICIs receiving FDA approvals starting with nivolumab in 2015