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aeruginosa -produced azurin can suppress cancer progression, which is supported by its ability to stabilize p53 by inhibiting constitutive photomorphogenesis protein 1-mediated ubiquitination and inducing cell cycle arrest at the G2/M phase after penetrating tumor cells

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In poultry, three principal categories of selenoproteins influence physiological function: thioredoxin reductases (TrxR), iodothyronine diiodinases, and glutathione peroxidases (GSH-Px)

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Abnormal Ca 2+ handling led to mitochondrial membrane permeabilization with consequent release of either mtDAMPs and MDVs to promote and sustain the inflammation or cytochrome c and pro-apoptotic factors to active caspases and trigger apoptosis, exacerbating the disease progression [24,25,26]