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Goshajinkigan (GJG), a traditional Japanese herbal medicine, has been evaluated in a randomized controlled trial showing that (GJG) has a neuroprotective effect and nerve-repairing effect in CIPN [60]

Hepatocellular carcinoma patients with low ITFG1 expression also present with better prognosis than those with high ITFG1 expression

Julio Ancochea declares that he has received funding for giving lectures at educational events and/or for scientific advice and/or research from Boehringer Ingelheim, Intermune and Zambon in relation to the subject of the guidelines

Mechanistically, we attributed the observed phenotype to impaired LXR alpha, PPAR gamma, and glucocorticoid receptor (GR) signalling

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The mature adipocytes secrete BMP4 that triggers preadipocyte differentiation by inducing the separation of Wnt1 inducible-signaling pathway protein 2 (WISP2) and zinc finger protein 423 (ZNF423), allowing ZNF423 to translocate into the nucleus and activate peroxisome proliferator-activated receptors (PPAR) and downstream cascade including CCAAT/enhancer-binding proteins (C/EBP), , and [41, 42] ( Figure 1 )