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This approach leads to selective oligodendrocyte stress and death, resulting in acute demyelination of distinct brain subregions, extensive microglial activation and astrocytic proliferation, a breakdown of the axonal transport mechanisms (Rhling, 2019), and, in more chronic models, overt axonal damage (Lindner, 2009)

Lupus (2018)

"Shifting the paradigm of testosterone and prostate cancer: the saturation model and the limits of androgen-dependent growth." Eur Urol

Cytoprotection: Studying the "organo-protective" effects on the gastrointestinal tract and internal organs

Because collagen III consists of homotrimers and the normal and mutant pro 1(III) chains appear to be produced in equal abundance, nearly 90% of all 1(III) trimers will contain one or more mutant -chains