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201 It is indisputable that reverse migration is a possible mechanism for the local resolution of inflammation and a potential new target for the pharmacological treatment of diseases characterized by neutrophil over-infiltration

Figure 6 Each bar represents the mean SEM, Effect of silymarin on time spent in the open-arm (upper panel) and closed arm (lower panel) of the elevated plus maze

Their data revealed dose-dependent increases in escape latency and progressive disorganization of hippocampal cytoarchitecture, including reduction of Nissl bodies and pyramidal neuron disruption that directly corresponded to cognitive performance decrements