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Generation and evaluation of isogenic IPSC as a source of cell replacement therapies in patients with Kearns Sayre syndrome

This may be because vitamin B12 plays a crucial role in the creation of serotonin - a neurotransmitter responsible for regulating our moods

Cham: Springer (2017) 13

To one medium, 16 L of Sodium Hydrogen L (+)-Glutamate monohydrate (Wako) dissolved in sterile water was added at final concentrations of 1, 5, 20, and 40 mM, and to the other medium, only 16 L of sterile water was added

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This enrichment, termed E0, was incubated at 25 C for 12 weeks and subsequently stored at 4 C for later use