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Cancer cells have also evolved the antioxidant defense system to protect themselves from excess ROS, but oxidative stress exceeding the antioxidant defense mechanism leads to cell death

Disulfidptosis: a new form of programmed cell death

doi: 10.3390/ani10071192 44 StanawayJ

In addition, regulatory T cells (Treg cells) and M2 macrophage fractions were significantly higher in poor response group while the fraction of activated NK cells and CD4 cells were substantially higher in disease control group

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Gao FSM, Chiu DAL, Motan Z, Zhang L, Chen HL, Ji HF, Tse QL, Fu Q, Lian