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Moreover, the accumulation of labeled metabolites was various among organs, as the liver was enriched mostly in lipids

The form, dose, and timing are worth recording, and further workup becomes necessary if the elevation persists once those sources are accounted for, or if symptoms, examination findings, or other labs raise concern

To further validate the functional role of the KEAP1NRF2 pathway, the Cis_NR T24 and J82 cells were treated with two distinct NRF2 pathway inhibitors, ML385 and R16 (refs

Previous studies find that knockout of OAT1 or OAT3 slightly reduces uricosuria, indicating that their essential function is urate excretion (Eraly et al., 2008)

It represents a more established regenerative option

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