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Med Sci Monit 26:e921276 Maida CD, Norrito RL, Rizzica S, Mazzola M, Scarantino ER, Tuttolomondo A (2024) Molecular pathogenesis of ischemic and hemorrhagic strokes: background and therapeutic approaches

Over the years, the usage of citrate as a buffer has reduced considerably for SC administration compared with the IV route, based on some (poorly studied, in the authors view) concerns on citrate formulation causing injection pain upon SC injection

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Supplementary Table 1)

Defects in some genes, like COL5A1 and the genes encoding the SLRPs, will produce alterations in fibril morphology, while others may produce the syndrome with minimal or no alteration in the fibril, as is the case for TNX defects

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