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Methods: Twenty-four adult male albino mice were used in this study

FTO sensitizes oral squamous cell carcinoma to ferroptosis via suppressing ACSL3 and GPX4

10f-THF: 10-formyltetrahydrofolate 5mTHF: 5-methyltetrahydrofolate AICAR: P-ribosyl-5-amino-4-imidazole carboxamide CH = THF: 5-10-methenyltetrahydrofolate CH2-THF: 5-10-methylenetetrahydrofolate Cys: cysteine Cysta cystathionine DHF: dihydrofolate DMG: dimethylglycine dTMP: deoxythymidine monophosphate dUMP: deoxyuridine monophophate GAR: glycinamide ribonucleotide Glut: glutamate Glut: Cys glutamyl-cysteine Gly: glycine

The supernatant containing free and reduced forms of Hcy labeled with ABDF can be used for analysis by HPLC

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American Roentgen Ray Society, 2011 Annual Meeting