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Did the pain subside

Always check with your practitioner for the right dosage, especially if you are pregnant, nursing, taking medication, or managing a medical condition

that is, if 14 patients were treated for 4 years with metformin 850 mg t.d.s., one would develop vitamin B12 deficiency

10.1021/jm100054f 41 FanM.YangK.WangX.WangY.TuF.HaT.et al (2020)

Direction of Future Research A multicenter randomized clinical trial is current in progress in Spain primary health-care setting called Project OB12 ( Conclusion Oral vitamin B12 replacement at 1000 g daily is an adequate alternative to IM B12 injections

It may be especially helpful for athletes, patients seeking rehabilitation, or individuals with high oxidative stress markers and inflammatory concerns