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This epigenetic memory enables adaptive evolution under therapeutic pressure, fostering heterogeneous subpopulations with enhanced drug tolerance, thus ultimately leading to therapeutic failure upon rechallenge [22]

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Methods Selection of studies for review The inclusion criteria for studies were defined as: (a) participants diagnosed with an autism spectrum disorder using standardised criteria such as the American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders (DSM)-IV-R [51] or the Childhood Autism Rating Scale (CARS) scores [52]

Basnet et al

In addition, the healed tendons are usually weaker than before injury

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