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Kyei NNA, Cramer B, Humpf HU et al (2022) Assessment of multiple mycotoxin exposure and its association with food consumption: a human biomonitoring study in a pregnant cohort in rural Bangladesh

Molecular and cellular research has shown that Gut dysbiosis (GD) influences PD progression by various pathways, including GBA, Toll-like receptors (TLR), Humoral immunity response (HIR), -synuclein accumulation and hypothalamicpituitaryadrenal (HPA) axis (11)

Following hyperosmotic stress, some ribosomal proteins that failed to properly fold can undergo ubiquitination, and RAD23B, a shuttle factor that has ubiquitin-associated domains, further drives LLPS of ubiquitinated ribosomal proteins and nuclear proteasomes, leading to proteasomal removal of misfolded ribosomal proteins

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In: Recent advances in therapeutic drug monitoring and clinical toxicology