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Data availability All data included in the Supplementary Information are available from the authors, as are unique reagents used in this article

326 The RaPID was prepared via a flexible in vitro translation system facilitated by flexible tRNA-aminoacylating ribozymes (named flexizymes), along with mRNA display technology

Science 340 , 12431246 (2013)

While at first glance the propensity for A aggregation appears to drive AD pathogenesis, this aggregation is one key function of the peptide and other similar amyloids in mounting an antimicrobial response, an effect most evident in the A 142 isoform