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However, the efficacy of copper peptides for skin care is often compromised by their hydrophilic nature, which hinders penetration through the stratum corneum, and their susceptibility to oxidation

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Its concentration in plasma declines significantly with age from approximately 200 ng/mL at age 20 to roughly 80 ng/mL by age 60

Nature 423 , 448452 (2003)

Copper serves as a cofactor for several enzymes your body relies on for repair work: lysyl oxidase for collagen and elastin cross-linking, superoxide dismutase for antioxidant defense, cytochrome c oxidase for cellular energy production, and tyrosinase for melanin synthesis

and modulates expression of thousands of genes, with studies showing it resets gene expression patterns toward a healthier, more youthful profile