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This is achieved via bioactive peptides synthesized by strains such as Lactobacillus helveticus and S

Consistently, ISL attenuated emodin-induced hepatotoxicity in vivo and in vitro through Nrf2 pathway (Ni et al., 2022)

The gut-brain axis and systemic inflammation have been implicated in the deposition of amyloid-beta plaques and tau pathology in the brain, both hallmarks of AD (Jia et al., 2024)

It was speculated that they might sense indirect cellular insults or act downstream of canonical NB-LRR proteins in disease resistance [171]