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Reactive oxygen species-scavenging nanomaterials for the prevention and treatment of age-related diseases

Immunity 18, 593603

We speculate that the emergence of the N-terminal hydrophobic region in vertebrates reflects a domain-gain event during evolution, which enabled neofunctionalization towards roles in mediating endoplasmic reticulum (ER) stress responses 54 and facilitating physical contacts between the ER and mitochondria 55

Inspired by NCL, in this work, we extended this approach and explored the use of 2-aminothiols for the deprotection of thiols bearing an acyl group

The funders had no role in the design of the study, in the collection, analysis, and interpretation of data, or in writing the manuscript

Neurological manifestations represent the most concerning complications of B12 deficiency and can become irreversible if left untreated