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Defects in the BCAA metabolism-related gene, protein phosphatase Mg 2+ /Mn 2+ -dependent 1 K (PPM1K), can disrupt energy metabolism homeostasis within the follicular microenvironment, potentially leading to PCOS-like phenotypes 15

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Specifically, significantly higher amounts of the pro-inflammatory cytokines IL-1 beta, IL-6, and IL-8, have been observed in the amnion and choriodecidua of patients in preterm labor than in women in spontaneous term labor

Regarding gastric secretion, the oral administration of QGC reduced gastric content significantly, dose-dependently, and prevented the development of reflux esophagitis

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