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Psychiatry 160 Ouellet-MorinI.OdgersC

Morgan, A

[DOI] [PubMed] [Google Scholar] Critchlow V, Liebelt RA, Bar-Sela M, Mountcastle W, Lipscomb HS

Usually, CD8+ T cells secrete cytotoxic molecules such as perforin and granzyme B to damage the islets directly, while CD4+ T cells do not generally exhibit cytotoxic activity, but it will help boost CD8+ T cells and secrete some pro-inflammatory cytokines such as tumor necrosis factor alpha (TNF-) and interferon gamma (IFN-) (7)