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Conversely, diminished antioxidant capacity (e.g., reduced SOD/GPx activity) is associated with -cell failure and poor glycemic control (Newsholme et al., 2019)

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To probe if the helicase additionally impacts nuclear egress, we performed a detailed analysis of the HSV-1 egress pathway by electron microscopy in the context of RNA interference targeting DDX3X, using the above 17 + viral strain

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Interestingly, the overall levels of nucleotides, CTP and TTP were significantly increased, up to 3-fold in HIF1 KO cells, in line with enhanced synthesis (Fig