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Restricted V alpha 2.3 gene usage by CD4+ T lymphocytes in bronchoalveolar lavage fluid from sarcoidosis patients correlates with HLA-DR3

In addition, microglia may respond to mechanically released chemokines such as the monocyte chemoattractant protein (MCP-1) from Mller glia (111) and fractalkine (CX3CL1) from ganglion cells (107)

Blood 112 , 11471150 (2008)

All these models (commonly referred to as fitness scores) are intended to evaluate the optimal risk/benefit ratio of a given therapy when delivered to a specific patient (5)