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doi: 10.3389/fphar.2025.1712869 Received 25 September 2025 Revised 13 December 2025 Accepted 17 December 2025 Published 07 January 2026 Volume 16 - 2025 Edited by Hua Chen, Ningxia Medical University, China Reviewed by Wenlong Sun, Shandong University of Technology, China Masanori Tamaki, Tokushima University, Japan Updates Copyright 2026 Ji, Li, Fang and Li

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Gene expression analysis in ARPE-19 cells was conducted by amplifying the following genes: SOD2 (protein name: superoxide dismutase 2, mitochondrial), CAT (protein name: catalase), HMOX1 (protein name: heme oxygenase 1), SNAL1 (protein name: Snail Family Transcriptional Repressor 1), ZEB1 (protein name: Zinc finger E-box-binding homeobox 1), TWIST1 (protein name: Twist Family BHLH Transcription Factor 1), VIM (protein name: Vimentin), FN1 (protein name: Fibronectin 1), ACTA2 (protein name: actin alpha 2, smooth muscle) and GAPDH (protein name: glyceraldehyde-3-phosphate dehydrogenase)

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ACL Recovery Post-Op A 29-year-old athlete recovering from ACL repair began the standard protocol (0.6mg daily) two weeks after surgery

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