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These observations support the view that (i) the expression of ectonucleotidases is linked to the production of ADO in the BM plasmatic fluid of MM patients and (ii) that metabolic reprogramming may allow mPCs to construct a microenvironment that favors their survival and protects them from the host immune system

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STROKE IN PATIENTS ON DIRECT ORAL ANTICOAGULANTS lvaro Laviana Marn 1 , Reyes De Torres-Chacon 1 , Juan Bautista Loscertales Castaos 1 , Emilio Montero Ramrez 1 , Antonio Bocero Garca 1 , Vctor Carmona Bravo 1 , Miguel Angel Gamero Garcia 1 , Ana Barragn 1 , Ana Dominguez Mayoral 1 , Soledad Prez Snchez 1 , Joan Montaner 1 1 Hospital Universitario Virgen Macarena, Servicio Andaluz de Salud, Seville, Spain Background and Aims: Despite the use of direct oral anticoagulants (DOACs) for stroke prevention, some patients continue to experience cardioembolic strokes

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