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Digestive Disorders Affecting the Small Intestine Conditions that damage or inflame the gut can reduce absorption, including: Celiac disease Crohns disease Small intestinal bacterial overgrowth (SIBO) Chronic infections (e.g., fish tapeworm) These conditions directly interfere with the ileum, where B12 is absorbed

While protocols vary widely, a common range for animal studies falls between 1-10 mcg per kg of body weight

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Impaired tumor growth and angiogenesis in mice heterozygous for Vegfr2 (Flk1)