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The main defense mechanisms include antioxidant enzyme systems (such as superoxide dismutase, catalase, and glutathione peroxidase) and non-enzymatic antioxidants (such as glutathione, vitamin E, and vitamin C) ( In sarcopenia, lipid peroxidation may impact muscle health through several pathways

Commentary: Maternal immune activation evoked by polyinosinic: polycytidylic acid does not evoke microglial cell activation in the embryo

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PubMed Central, Baranova, Tatyana, et al

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In contrast, however, our results demonstrate increased oxidative stress and reduced expression of synaptic proteins 1-week post ICV-STZ injection