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The three SSP enzymes (PHGDH, PSAT, and PSPH) are all highly expressed in various cancers to meet the large serine demand for survival (Locasale et al., 2011

After centrifugation at 13,000 rpm for 10 min at 4C, 200 l of the supernatant was transferred to a new tube and was subjected to acid hydrolysis by adding 600 l 1 M HCl and incubation at 94C for 2 h

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Besides GSH conjugation, several activities were found to be associated with GSTs in both plant and animal system such as high steroid isomerase activity, leukotriene biosynthesis, formation of oxylipins (precursor of jasmonic acid), double bond cis/trans isomerization, michael addition, mesotrione degradation, dehydroascorbate reduction, non-catalytic ligand binding and transport, signal transduction [5] and protection against ozone damages [6]

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The applicant stated that the distal tip of the LithoVue TM ( Elite Ureteroscope's shaft includes the working channel, the illumination optics, the digital imaging sensor, and a Micro-Electro-Mechanical Systems (MEMS) pressure sensor for monitoring the real-time intraluminal pressure during ureteroscopy