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In this study, dietary SILY supplementation was associated with a mitigation of DEX-induced changes in brain oxidative stress, antioxidant status, and inflammatory markers

Inhibition of DHODH cannot increase the sensitivity of cells to FIN56-induced ferroptosis, while the decrease in CoQ cells was more sensitive to ferroptosis than DHODH knockout cells

Funding This work is supported by research grants from the Canadian Institute of Health Research (MOP 201803PJ8) and the Alzheimers Association (PTC-18-543823) and made possible by Part the Cloud, as well as the Alzheimer Society Research Program (ASRP #21-11)

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This water-soluble vitamin is pivotal in various bodily functions, including red blood cell formation, nerve function, and DNA synthesis

Serotonin and Dopamine: In models of insomnia, DSIP administration has been observed to restore depleted levels of serotonin (5-HT) and dopamine, correcting the neurochemical imbalances driven by sleep deprivation