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In the United States, the compound's unapproved status also intersects with compounding policy: the FDA has publicly categorized BPC-157 among substances it has flagged for pharmacy compounding review, reflecting the agency's position that available data are insufficient to support that use

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The most common reports are mild redness at the injection site, occasional small bumps that resolve on their own, and sometimes a few days of fatigue at the start as AMPK activation ramps up

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