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Exposure of H69 cells to 50mM AA induced KRT19 (proliferation marker), cholangiokines ( IL1B, CCL2 , TNF) mRNA, which was prevented by GW4064 co-incubation

After a person is diagnosed with Lyme disease, Epstein-Barr virus, or other chronic infections, their blood is sent to a laboratory where a specific oligonucleotide therapy is created

CRC patients exhibit marked alterations in gut microbiota composition and distribution, characterized by reduced beneficial bacteria and increased pathogenic species

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doi: 10.1016/j.biopsych.2017.08.017 99

In line with this, cells with individual TET gene knockdown exhibited reduced cytosolic NADPH levels and increased sensitivity to glucose starvation, which could not be rescued by antioxidants (NAC or catalase) (Extended Data Fig