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In the past few years, significant experimental efforts have been put forward to explore the relationships between cellular oxidative processes and the modulation of cell signal transduction, collectively grouped under the concept of redox signaling (848)

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Their treatment plan may differ from the recommendations listed below due to factors like: underlying medical conditions age deficiency severity For example, the following are global recommendations for treating vitamin D deficiency rickets in infants and children ( Under 3 months old: 2,000 IU (50 mcg) oral supplements daily for 3 months Infants between 2 and 12 months old: 2,000 IU (50 mcg) oral supplements daily for 3 months or a single dose of 50,000 IU (1,250 mcg) Children 12 months to 12 years old: 3,0006,000 IU (75150 mcg) oral supplements daily for 3 months or a single dose of 150,000 IU (3,750 mcg) Children over 12 years old: 6,000 IU (150 mcg) oral supplements daily for 3 months or a single dose of 300,000 IU (7,500 mcg) After vitamin D levels have normalized, its recommended that babies under 12 months old receive a daily maintenance dose of 400 IU (10 mcg), while children 1 year or older receive a daily dose of 600 IU (15 mcg) ( Its also recommended that children and teens with vitamin D deficiency rickets maintain a daily calcium intake of at least 500 mg per day

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