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doi: 10.3389/fphys.2021.772894 [DOI] [PMC free article] [PubMed] [Google Scholar] 252

Key finding: AOD 9604 (0.1-10 mcg/kg) promoted cartilage repair with 52% defect filling versus 8% in controls

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This sustained receptor occupation produces a prolonged elevation of both GH and IGF-1 compared to injectable secretagogues