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In late-life depression, variability in symptom presentation and treatment response arises from interacting neurotransmitter, inflammatory, and neurodegenerative processes and potentially other molecular mechanisms that impair synaptic plasticity

Finally, we demonstrated that depletion of glutathione caused inhibition of the NF-kB pathway

and R is selected from the group consisting of an NH 2 moiety, alkyl moieties containing from 1 to 18 carbon atoms, aryl moleties containing from 6 to 12 atoms, alkoxy moleties containing from 1 to 18 carbon atoms, aryloxy moleties containing from 6 to 12 carbon atoms, alkylamino moieties containing from 1 to 18 carbon atoms, or where R is L-prolyl-L-valyl-L-phenylalanyl-L-valine, L-valyl-L-phenylalanyl-L-valine, L-tryptophan, or (glycyl)n-L-tryptophan where n=1-4

Ministry of Food and Drug Safety, South Korea Baker MT, Lu P, Parrella JA, Leggette HR (2022) Consumer acceptance toward functional foods: a scoping review

L.Pozzo-MillerL.et al