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Although the pooled analysis did not show a statistically significant association, a consistent trend toward increased breast cancer risk, particularly in C282Y homozygotes, was observed

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Nrf2 transcriptionally activates GGT [29], which plays a key role in glutathione homeostasis by breaking down extracellular glutathione into its constituent parts, which can be taken up by the cell for intracellular glutathione synthesis [30]

Numerous studies have linked folate intake to a reduced risk of some cancers, including colorectal cancer, while folate deficiency has been shown to increase the risk of cancer

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Endogenous redox sensors ( e.g