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Introduction Parkinsons disease (PD) is characterized by the progressive loss of dopaminergic neurons in the substantia nigra par compacta (SNpc) and by impairments in motor function as well as other autonomic nervous system activities (Yamada et al., 2001

In an August 2018 article, a team of Auburn University veterinary researchers examined the effectiveness of S/V in 7 dogs diagnosed with MVD, compared to 6 MVD-affected dogs in the placebo group

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While probiotics such as Bifidobacterium and Lactobacillus have shown potential in restoring gut microbial balance and modulating immune responses, their clinical application remains largely isolated, often lacking synergistic prebiotic supplementation (Ouyang et al., 2024)