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It bypasses first-pass hepatic metabolism which oral delivery does not allowing a greater proportion of the absorbed peptide to remain intact as it enters circulation.7 The olfactory pathway also provides a potential direct nose-to-brain route, bypassing the blood-brain barrier a property that has generated interest for neuropeptides and potential neurological applications

Since researchers will likely not be using the entire solution immediately, it can be store it in a refrigerator at a temperature of 2-8C (36-46F) to ensure its stability [23]

Not intended for injection, ingestion, or clinical applications

Safety-wise, intramuscular B12 is generally well tolerated

Vitamin supplements are very popular, not just vitamin B12 but supplements for all vitamins

Our experience shows that failure to refrigerate is the single most common cause of compromised research materials