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Similarly, dandelion polysaccharide inhibited the JAK-STAT signaling pathway and reduced iron element expression in a murine model, reducing the iron load and hepatocellular carcinoma (HCC) process (159)

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We propose that chronic exposure to mutant huntingtin (HTT) elicits a trajectory of impaired mitochondrial biology that maximally impacts subsets of mitotypes abundant in the striatum and cerebral cortex, which eventually surfaces as the hallmark features of HD