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b , Glucose tolerance test (GTT) and insulin during the GTT at 3 months of age (n = 6 Control and 5 NDI1)

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As a result, intestinal tumors from Apc +/Min /Stard7 IEC mice are expected to be less sensitive to serine deprivation, as previously described for K-Ras-driven intestinal tumors (Maddocks et al, 2017)

Protein extraction and western blot analyses Serum-starved NP cells were treated with without 5 molL 1 of the TGF R1 kinase inhibitor, LY364947, for 2 h and then stimulated with conditioned media from DFbs for 30 mins

That data wasnt always included in the FDA scientists presentations a decision that rankled some committee members