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While NPs like salvianolic acid show preclinical antifibrotic activity, their undefined targets and pharmacokinetics hinder clinical adoptiona stark contrast to approved synthetics like pirfenidone (2,403 mg/day) (Noble et al., 2011) and nintedanib (300 mg/day) (Richeldi et al., 2014), which themselves face tolerability limitations (Raghu et al., 2022a)

Markoullis, K

However, there is a lack of clinical data to either support or refute these recommendations

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PubMed Central, Stajnko, Anja, et al

"L-Theanine: A Unique Functional Amino Acid in Tea (Camellia sinensis L.) With Multiple Health Benefits and Food Applications." Front Nutr