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Thiamine (vitamin B1) in the human body, as a result of phosphorylation processes, is converted into cocarboxylase, which is a coenzyme of many enzymatic reactions

Our bodies are complex systems of nerves, muscles, and bones working together to keep us moving and functioning

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In both trials, people on Zepbound lost, on average, around 20% of their body weight, which Lilly suspects contributed to the reduction in sleep apnea events

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Both are well-studied individually in preclinical models