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doi: 10.1016/j.phrs.2022.106242 84 Metabolic modulation of immune checkpoints and novel therapeutic strategies in cancer

Recombinant proteins are bound by fusion tags to specific ligands encapsulated on a solid phase matrix, allowing for targeted immobilization and purification of recombinant proteins, greatly simplifying the detection of recombinant proteins

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Depending on the timing of metastatic seeding, the extent to which the primary tumour and established metastases evolve will vary