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Radiologic evaluation was based on modified Response Evaluation Criteria in Solid Tumors (mRECIST)

To show the enzymatic region that binds substrates (H-site of GSTP1), we have included the structure of the anticancer drug chlorambucil reproducing the same binding position as in its co-crystal with GSTP1 (PDB structure 21GS)

Capecitabine and temozolomide versus FOLFIRI in RAS-mutated, MGMT-methylated metastatic colorectal cancer

Peer review Peer review information Nature Reviews Bioengineering thanks Korkut Uygun, who co-reviewed with Raphaela Bento

Brightens Dull Skin Environmental pollution, stress and sun exposure can make skin appear tired and lifeless

To achieve skin that looks more radiant, clear, and smooth, use it consistently within a routine that includes gentle cleansing, suitable hydration, and daily sun protection