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While symptoms often resolve with treatment or drainage, in some cases, inflammation from the infection can contribute to chronic tinnitus

Molecular actions include both inhibition and activation of proteins, mutagenesis of DNA and activation of gene transcription

Trends Endocrinol Metab (2019) 30:47990

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While deletion of this region did not alter the stability of the Bd GUS mutant, as assessed by CD-monitored thermal denaturation, it rendered the enzyme inactive with p NPG, preventing further inhibition studies (Figs S13a and S15d)