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Additionally, knockout of nicotinamide adenine dinucleotide phosphate (NADH) dehydrogenase ubiquinone 1 subcomplex (NDUFB)8 in combination with ICI led to slower tumor growth compared to WT NDUFB8 groups treated with anti-PD-L1

A large polycarbonate box was used to conduct this test, which was divided into three compartments by two movable walls

The complex II - III activity (Figure 5C) increased in the HF6+AVO + D and HF12 + AVO groups in comparison to the HF6 and HF12 groups, respectively

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This enrichment corresponds with increased cytokine and chemokine activity and immunoglobulin Fc-gamma receptor I complex binding that may further inflammation (Arbaizar-Rovirosa et al., 2023)

Logistic regression analysis was used to evaluate whether a patients age, sex, race, cancer type, checkpoint inhibitor received, and checkpoint inhibitor doses received predicted the occurrence of immune-related adverse events