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Description

Mutation of an active site nucleophilic histidine to asparagine (human H112N

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Bcl-2 family proteins play a key role in the regulation of mitochondrial membrane permeability and the release of apoptosis factors, while caspase protease, especially Caspase-3, acts as an apoptosis effector molecule to activate downstream apoptosis-related proteins and destroy cytoskeleton and housekeeping gene functions

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