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For RA and T1D, given limited evidence from small-sample clinical studies or preclinical models, these interventions are currently in the exploratory stage and not recommended to replace conventional immunomodulators

Its cytoprotective effects in gastrointestinal tissue have been linked to interactions with prostaglandin and dopamine systems

*Correspondence: Abdel Qawasmeh, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers