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most patients report no downtime and can resume normal activity immediately

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It demands the same level of focus and sterile discipline as any other part of your experiment

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VB12 is a water-soluble vitamin, and when ingested in its free or nonprotein-bound form, will bind to carrier proteins known as R-binders (transcobalamin I) secreted by salivary glands in the oropharynx, and gastric mucosal cells within the stomach [6]

In this study, mice were given equivalent quantities of cuprizone regardless of feed formulation, and feed was replenished in line with standard protocols 34,39 , therefore it is likely that the observed differences between formulations is due to differences in consumption of the feed between different formulations