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Carnitine has been supplemented in a great variety of patients, such as inborn errors in the carnitine system, mitochondrial beta oxidation, mitochondrial acyl-CoA-linked enzymes, oxidative phosphorylation [35,84], in cardiovascular diseases [85], AIDS [60], in diabetes mellitus [86], chronic fatigue syndrome [87], chemotherapy- [88] and interferon-a- [89] induced fatigue, children with ADHD [90]

The findings from FIELD, ACCORD-EYE, and LENS are shown comparatively in Table 1

In 2023, an estimated 28.9 million U.S

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doi: 10.3389/fcell.2018.00023 70 TsaiCCWuSBChengCYKaoSCKauHCChiouSHet al

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