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Interestingly, exposure to PQQ leads to increased butyrate levels [137,140], most likely because it is used preferentially as a cofactor for membrane-bound hexose and alcohol dehydrogenases in E

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Chronic inflammation, often associated with autoimmune diseases, is both a cause and a consequence of leaky gut, creating a cycle of dysfunction.4 Nutritional deficiencies, particularly in zinc, vitamin D, vitamin A, and certain amino acids may also hinder the gut's ability to repair itself

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