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3xTg mice have consistently been shown to have impairments in hippocampal-dependent tasks such as Barnes Maze and NOR with memory deficits becoming apparent as early as 4-6 months of age and growing more severe with increasing age 13,59

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PD patients received 10 days of rTMS (once daily, 10 Hz to the rDLPFC)

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Icariside I enhances beneficial gut bacteria, upregulates immune cells, and inhibits melanoma (B16-F10) cell growth [760, 761]

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