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A., & Chenery, S

10.1016/j.neuropharm.2014.10.028 Neuropharmacology 87 OuardouzM.CoderreE.ZamponiG

For example, H 2 O 2 /O/OH/ 1 O can impair DNA synthesis substrate function by oxidizing nucleotide precursors, including dATP and dGTP [207]

From this synthesis, we propose restoration of copper balance using copper delivery agents in combination with chaperones/chaperone mimetics, perhaps in conjunction with the neuroprotective amino acid serine, as a promising strategy in the treatment of this incurable disease